| 许姗姗,刘增智,李文利.芽孢杆菌生物被膜形成分子调控机制的研究进展[J].中国海洋药物,2019,38(5):61-68. |
| 芽孢杆菌生物被膜形成分子调控机制的研究进展 |
| Recent Advances on Regulation Mechanisms of Biofilm Formation of Bacillus |
| 投稿时间：2019-04-30 修订日期：2019-05-10 |
| DOI： |
| 中文关键词: 枯草芽孢杆菌，生物被膜，分子调控机制，调控基因 |
| English Keywords:Bacillus subtilis biofilm molecular regulatory mechanism regulatory gene |
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| 中文摘要: |
| 生物被膜是微生物为了适应自然界环境变化而形成的,是微生物一种常见的生存状态。芽孢杆菌在海洋环境中分布广泛,许多菌株能够产生复杂的生物被膜,使得它们在生物防治方面具有巨大的应用潜力。目前关于芽孢杆菌生物被膜的研究主要是以模式菌株枯草芽孢杆菌为研究对象。本文综述了目前对枯草芽孢杆菌形成生物被膜的分子调控机制研究所取得的重要进展,包括Spo0A调控机制,SinR-SlrR开关调节系统,DegS-DegU双组分系统,同时介绍了Abh,Veg,RemA等参与的调控机制。 |
| English Summary: |
| Biofilm is a common living state of microorganisms, whose formation is a strategy by which microorganisms survive and adapt to the environmental conditions. Bacillus strains are widely distributed in the marine environment, and some of them can produce complex biofilms, having great potential for application in biological control. At present, the researches on regulation mechanisms of Bacillus biofilm formation mainly focuses on the model strain Bacillus subtilis. This paper reviews the recent progresses in the molecular regulation mechanism of biofilm formation of Bacillus subtilis, involving well-studied Spo0A, SinR-SlrR switch, two-component system DegS-DegU, as well as Abh, Veg and RemA. |
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