| 吴丽娟,赵峡,王伟.海洋硫酸多糖抗病毒作用机制和构效关系D[J].中国海洋药物,2016,35(4):87-92. |
| 海洋硫酸多糖抗病毒作用机制和构效关系D |
| Antiviral mechanisms and structure-activity relationshipsof marine sulfated polysaccharides |
| 投稿时间：2015-08-05 修订日期：2015-09-08 |
| DOI： |
| 中文关键词: 海洋硫酸多糖 抗病毒机制 构效关系 |
| English Keywords:marine sulfated polysaccharide antiviral mechanism structure-activity relationship |
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| 中文摘要: |
| 近年来大量的研究表明,海洋硫酸多糖具备广泛的抗病毒活性,且抗病毒作用机制多样,并与其复杂的结构特性密切相关。海洋硫酸多糖的抗病毒作用机制及构效关系研究已成为人们关注的热点。本文对目前发现的海洋硫酸多糖抗病毒活性、作用机制及构效关系进行了综合阐述,以期为新型抗病毒硫酸多糖药物的研发提供指导和参考。 |
| English Summary: |
| Marine sulfated polysaccharides have been demonstrated to exhibit broad antiviral activities in recent years. The antiviral mechanisms of marine sulfated polysaccharides are of great diversity. The relationships between structures and antiviral activities are complex. The antiviral mechanisms and structure-activity relationships of marine sulfated polysaccharides have been paid great attentions in life science field. This paper reviewed the antiviral activities, antiviral mechanisms and structure-activity relationships of marine sulfated polysaccharides that have been reported in recent years. This information will be helpful for the research and development of new antiviral drugs. |
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