张文源,高保燕,雷学青,等.岩藻黄素的理化与生物学特性、制备技术及其生理活性研究进展[J].中国海洋药物,2015,34(3):81-95.
岩藻黄素的理化与生物学特性、制备技术及其生理活性研究进展
Progress in physicochemical and biological properties, preparation techniques and physiological acitivities of fucoxanthinWenyuan ZHANG1, Baoyan GAO1, Xueqing LEI1, Aifen LI1, Jie WU2*, Chengwu ZHANG1*
投稿时间:2014-10-10  修订日期:2015-01-15
DOI:
中文关键词:  岩藻黄素  理化性质与生物学特性  生物合成途径  提取与分离纯化技术  生理活性
English Keywords:Fucoxanthin  Physicochemical and Biological Properties  Biosynthetic Pathway  Extraction and Purification Technique  Physiological Activity
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作者单位E-mail
张文源 暨南大学 1146967826@qq.com 
高保燕 暨南大学  
雷学青 暨南大学  
李爱芬 暨南大学  
吴洁 中国药科大学  
张成武* 暨南大学 tzhangcw@jnu.edu.cn 
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中文摘要:
      岩藻黄素,又称岩藻黄质或褐藻黄素,是一种脂溶性色素,为胡萝卜素的含氧衍生物,含有一个多烯烃骨架,属于丙二烯型类胡萝卜素。它主要来源于异鞭藻门的褐藻和硅藻以及定鞭藻门的藻类。本文介绍了岩藻黄素的理化性质、生物学特性及其生物合成途径,并对岩藻黄素经典的与现代绿色的提取方法以及多种分离纯化技术进行了详细介绍。同时对岩藻黄素的各种生理活性,包括抗炎、抗肿瘤、抗肥胖、抗氧化、抗痘、抗糖尿病、抗疟疾和抗血脂等方面的研究进展进行了综述性的报道。
English Summary:
      Fucoxanthin, a lipid-soluble pigment, is the oxygenated derivative of carotene,which contains the polyene backone and belongs to the allenic carotenoid. Fucoxnathin is mainly originated from the heterokontophytes, such as brown algae and diatoms, and the haptophytes. This review article presented the physicochemical and biological properties of fucoxanthin, as well as the biosynthetic pathway of fucoxanthin, and compared the traditional extraction and purification methods with the novel preparation techniques of fucoxanthin in details. The current research progresses in various physiological activities of fucoxanthin, which include anti-inflammatory、anti-neoplastic、anti-obesity、antioxidant、anti-acne、antidiabetes、antimalaria and antilipemic, etc, were also reported in this paper.
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