| .文蛤多糖抗癌免疫药理作用的研究[J].中国海洋药物,1999,18(2):15-19. |
| 文蛤多糖抗癌免疫药理作用的研究 |
| AN EXPERIMENTAL STUDY ON THE EFFECTS OF MERETRIX POLYSACCHARIDE ON ANTINEOPLASTIC AND IMMUNORGULATION |
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| DOI： |
| 中文关键词: 文蛤多糖 免疫调节 抗癌药 |
| English Keywords:Meretrix polysaccharide,antineoplastic,immunoregulation |
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| 中文摘要: |
| 小鼠ｉｇ文蛤多糖１００ｍｇ／ｋｇ、２００ｍｇ／ｋｇ，显著抑制Ｓ１８０实体瘤的瘤重显著延长ＥＡＣ腹水瘤荷瘤小鼠的生存时间，对Ｌ１２１０白血病的存活时间无明显影响，以环磷酰胺损伤小鼠的免疫功能，上述剂量的文蛤多糖可使免疫指标显著改善阻挡的增重，白细胞数量增多，在噬能力增强，血清溶血素水平增高，ＳＲ－ＢＣ－ＤＴＨ和ＰＣ－ＤＴＨ反应增强，以上结果表明，文蛤多人有抗癌作用和免疫调节作用。 |
| English Summary: |
| The results indicated that Meretrix polysaccharide (was given orally, 100mg/ kg. 200mg/kg ) could remarkably reduce the weight of S_(180) solid carcinoma in mice, prolong the survival period of mice with EAC ascites carcinoma and hepatic carinoma. It had no effect on L_(1210) leukemia. It also showed that Meretrix polysaccharide could significantly improve the Index of thymus and spleen, Increase the number of leukocyte, improve the phagocytic power, increase the production of serum hemolvsin and enhance the SRBC DTH and PC-DTH reac- non in immunodepressed mice induced by cvclophosphamide. It is suggested that Meretrix polysaccharide has effects on antineoplastic a.d immunoregulation. |
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