| .海洋生物敷料伊特安的止血和促愈合作用[J].中国海洋药物,1997,16(4):20-23. |
| 海洋生物敷料伊特安的止血和促愈合作用 |
| EXPERIMENTAL STUDIES ON HAEMOSTASIS AND HEALING PROMOTION EFFECT OF ETAN |
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| DOI： |
| 中文关键词: 甲壳胺 海洋生物 敷料 生物相容性 止血 愈合 |
| English Keywords:chit osan,biological compatibility,hemostasis,healing promotion jbiomaterial |
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| 中文摘要: |
| 伊特安是采用海洋生物的甲壳提取甲壳受发泡等工艺制成的生物性敷料，本实验采用家兔烫伤皮肤模型，切割静脉压迫止血方法以及皮下埋植观察其吸渗止血，促进愈合和生物相容性，实验结果表明，伊特安能促进愈合作用，缩短创面结痂时间，使创面皮肤组织迅速愈合和较好的吸渗止血作用，且明显优于明胶海绵的吸渗止血作用，伊特安皮下埋植２ｗ能与皮下组织融合４ｗ后皮肤组织恢复接近于正常皮肤组织，表明该品具有较好的生物相容性。 |
| English Summary: |
| ETAN is a marine biomaterial which is made of chitosan,a partially deacetylated derivative of chitin ,and prepared by a foaming technique. The effects of absorbing exudate, stopbleeding,promoting wound healing and biological compatibility were observed in this experiment. The results showed ETAN could promote skin wound healing reduce the scab time of the wound surfaces. Skin tissue was healed quickly after ETAN was coated on wound skin surfaces,and it had marked effects of absorbing exudate,and haemostasis. Its effects were superior to that of gelatin sponge. ETAN could be fused with subcutaneous tisssue embeded subcutaneously two weeks later. The fused skin tissue was returned to normal skin tissue nearly after it was embeded four weeks . These experimental results showed ETAN had a better biological compatibility. |
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