.文蛤肉水解液降血脂作用的实验研究[J].中国海洋药物,1997,16(2):21-24.
文蛤肉水解液降血脂作用的实验研究
A STUDY ON HYPOLIPEMIC EFFECT OF HYDROLYSATE OF MERETRIX MERETRIX SOFT TISSUE IN QUAIL
  
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中文关键词:  文蛤 水解液 药效 高脂血症
English Keywords:Meretrix meretrix,blood lipidsiblood viscosity iplatelet aggregation
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中文摘要:
      高脂血症鹌鹑口服文蛤肉水解液20、10g/kg2w后,能明显抑制血清总胆固醇(TC)和甘油三酯(TG)的升高,提高主密度脂蛋白胆固醇(HDL-C)的含量。4W后,能不同程度地肝胆固醇及TG含量;给药3W后,对正常及高脂血症鹌鹑的全血粘度均有降低作用,并且能抑制家兔体外ADP诱导的血小板聚集。结果显示,文蛤肉水解液具有明显降血脂、降低血液粘度及抑制血小板聚集的作用。
English Summary:
      Hydrolysate of Meretrix meretrix soft tissue (HMST ) (20, 10g/kg ,po.for 14d ) could markedly inhibit the increase of serum total cholesterol(TC)and triglyceride(TG),enhance the content of high density lipoprotein cholesterol(HLD-C) ;reduced cholesterol(Ch)of the liver(for 28d)in hyperlipimic quail ;and it could also reduce whole blood viscosity in normal and hyperlipemic quail (for 21d).In addition.it could suppress the platelet aggregation induced by ADP in rabbits in vitro. The results show that HMST obviously decreased blood lipid and whole blood viscosity .inhibited platelet aggregation.
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