| .甘糖酯对肺心病患者抗氧化作用机制的探讨[J].中国海洋药物,1997,16(1):50-52. |
| 甘糖酯对肺心病患者抗氧化作用机制的探讨 |
| AN EXPLORATION ON THE MECHANISM OF ANTIOXIDANT EFFECT OF PGMS IN PATIENTS WITH CHRONIC COR-PUL-MONALE |
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| 中文关键词: 肺心病 甘糖酯 抗氧化作用 海洋药 中医药疗法 |
| English Keywords:heparinoid,PGMS,glutathione peroxidase,superoxide dismutase,catalase,lipoxygenase,obstructive lung diseases |
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| 中文摘要: |
| 慢性肺心病３６例，随机分为２组，甘糖酯组１８例在常规治疗基础上加用ＰＧＭＳ２００ｍｇ于５％葡萄糖氯化钠注射液５００ｍｌ中静滴，ｑｄ，共１０ｄ。并与常规治疗组１８例对照。结果：治疗后２组脂质过氧化物的均显著降低。谷胱甘肽过氧化物酶及过氧经氢酶均显著升高；经组间比较，ＬＰＯ的 |
| English Summary: |
| 36 patients with chronic cor pulmonale were divided into 2 groups at random. 18 patients (M14, F4; age 65 11 y) received proplylene glucol mannurate sulphate (PGMS) 200 mg in 5% glucose in normal saline 500 ml iv drip qd and 18 patiants (M 13. F5? age 67 6 y) received routine treatment served as control, all were treated for 10 d. The values of glutathione peroxidase (GSH-Px), catalase (CAT) and GSH-Px/LPO (lipoper-oxide) in 2 groups were all increased distinctly, the level of LPO in 2 groups fell ( P <0. 01). But the increase of CAT and the decrease distinctly, the level of LPO in PGMS group were greater than those in routine treatment group ( P <0. 05). |
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