复方鱼油口服制剂的促智作用

.复方鱼油口服制剂的促智作用[J].中国海洋药物,1997,16(1):26-29.

复方鱼油口服制剂的促智作用

EFFECTS OF COMPOUND ORAL FISH OIL PREPARATION ON INCREASE OF INTELLIGENCE

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English Keywords:oral fish oil preparation,learning and memory,step-down test,normobaric hypoxia test,loaded swimming test

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中文摘要:

采用小鼠跳台法、常压缺氧和小鼠负重游泳等实验,初步观察了复方鱼油口服制剂对正常小鼠学习、记忆、耐缺氧能力等方面的影响。结果表明:复方鱼油口服制剂低剂量和高剂量(分别相当于含精制鱼油3.6g/(kg·d)和7.2g/(kg·d)ig×15d和ig×30d后均对小鼠的学习、记忆有明显的的改善,与空白对照组相比,表现出记忆力增强,灵敏性提高。此外,30d后,复方鱼油口服制剂具有一定的提高耐缺氧能力和抗疲劳作用。连续给药期间,鱼油组体重与对照组体重增长相似。

English Summary:

The effects of compound oral fish oil preparation on the increase of intelligence were studied. Step-down test, normobaric hypoxia test and loaded swimming test in mice were used. The results indicated that during the administration period (15 d and 30 d), the oral preparation containing fish oil 3. 6 g/kg and 7. 2 g/kg increased both learning and memory abilities, promoted the tolerance of normal mice to hypoxia as well as swimming fatigue.

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