| .园背角无齿蚌抗肿瘤有效成份的研究：ⅠHB—Ⅱ糖蛋白的分析鉴定[J].中国海洋药物,1997,16(1):23-25. |
| 园背角无齿蚌抗肿瘤有效成份的研究：ⅠHB—Ⅱ糖蛋白的分析鉴定 |
| STUDIES ON ANTITUMOR EFFECTIVE CONSTITUENT OF ANODONTA WOODIANA LEAI Analysis and Characterization of Glycoprotein HB- II |
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| DOI： |
| 中文关键词: 蚌 糖蛋白 抗肿瘤 园背色无齿蚌 有效成分 |
| English Keywords:glycoprotein,antitumor,Anodonta woodiana Lea, |
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| 中文摘要: |
| 对ＨＢ有效组份分离，纯化得到ＨＢ－Ⅱ，经不连续聚丙烯胺园盘电泳检查，显示一条色带，用凝胶柱层法测定共ＭＷ为１７９００Ｄ，用园盘等电聚焦法测定其ＰＩ值为４．７６，该成份含蛋白质４７．２３％，含糖为２１．１７％，含硫酸基０．４４％，推测其为一种糖蛋白，该成份具有抗肿瘤活性。 |
| English Summary: |
| An antitumor glycoprotein (HB) was obtained by separation and purification. It showed only one band by discontinual discoelectrophoresis. The pI of HB is 4. 67 when determined by discoisoelectric focusing. The M W of HB- I is 17 900 D by sephadex G-100 chromagraphy. It contained carbohydrates (21.17%), protein (47. 23%) and sulphate group (0.44%). |
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