| .金蓝宝对小鼠免疫功能的影响[J].中国海洋药物,1996,15(2):7-11. |
| 金蓝宝对小鼠免疫功能的影响 |
| THE INFLUENCE OF JINLANBAO ON IMMUNOLOGICAL FUNCTION IN MICE |
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| DOI： |
| 中文关键词: 海湾扇贝 免疫增强剂 细胞免疫 金蓝宝 海洋药 |
| English Keywords:Argopecten irradiaus,immunopotentiator,cellular immunity,humoral immunity |
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| 中文摘要: |
| 金蓝宝是以９海湾扇贝为主成分配以部分中药，提取制成，毒性和病亘试验显示，动物脾脏有增生活跃相，胸腺出现轻度增生。因此，又对动物免疫系统进行试验，发现ＪＬＢ对由甲基泼尼松抑制的小鼠巨噬细胞吞噬功能，有显著提高尤其小是剂量亦有明显的免疫增强作用。 |
| English Summary: |
| JINLANBAO (JLB), a preparation extracted from the Pecten Argopecten irradiaus and some Chinese medicinal herbs,has been reported to have several immuno-mod-ulatory effects in mice In this paper,the influence of JLB on the immuivlogcai functions in mice is presented. The results showed that JLB could enhance the phagocytosis of intraperi-toneal macrophages (Mo) inhibited by methyl-prednisone,increase the IgM level in CTX-de-pressed cells in a dose-dependent manner in the medium-dose and high-dose group. JLB has been found to have a two-way regulatory effect on ConA-induced T-lyrophocytes prolifera tion, tea promoting effect in low dose group,and an inhibiting effect in high dose group. As an immunopotentiator, the potential values and prospects for the developing of JLB should be paid attention to in pharmaceutical sciences. |
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