.甘糖酯,藻酸双酯钠对急性脑梗死患者白细胞变形能力的影响[J].中国海洋药物,1994,13(4):20-22. |
甘糖酯,藻酸双酯钠对急性脑梗死患者白细胞变形能力的影响 |
EFFECTS OF PGMS AND PSS ON LEUCOCYTE DEFORMABILITY IN PATIENTS WITH ACUTE CEREBRAL INFARCTION |
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DOI: |
中文关键词: 白细胞变形能力 甘糖酯 藻酸双酯钠 脑栓塞 |
English Keywords:Acute cerebral infarction (leucocyte deformability,microcirculation,PGMS,PSS |
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中文摘要: |
本文观察了急性脑梗死患者白细胞变形能力的变化及甘糖酯(PGMS)和藻酸双酯钠(PSS)对其影响。结果显示,急性脑梗死患者白细胞IF较对照组明显增高(P<0.001)。白细胞体外孵育2h后,其IF较孵育前明显增高(P<0.001),但加PGMS和PSS孵育的白细胞IF较空白对照管明显降低(P<0.001),且随着药物含量的增加IF逐渐减低,其中以PGMS作有较明显。结果提示,PGMS和PSS具有明显改善白细胞变形能力的作用,对改善急性脑梗死患者微循环,增加缺血脑组织的血流量,缩小梗死面积有重要的意义。 |
English Summary: |
The changes of leucocyte deformability (LD) and effects of PGMS and PSS on LD in patients with acute cerebral infarction (ACT) were observed. The results showed that leucocyte filtration index (IF) was higher significantly in patients with ACI than that in the normal control ( P |
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