| .羊栖菜多糖对L_(615)小鼠LPO含量及GR、GSH—PX、CAT和SOD活性的影向[J].中国海洋药物,1994,13(2):. |
| 羊栖菜多糖对L_(615)小鼠LPO含量及GR、GSH—PX、CAT和SOD活性的影向 |
| EFFECTS OF SFPS ON CONTENTS OF LPO AND ENZYME ACTIVITIES OF GR, GSH- PX, CAT AND SOD IN LEUKEMIA L_(615) MICE |
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| DOI： |
| 中文关键词: 羊栖菜多糖,L_(615),小鼠,脂质过氧化物,过氧化氢酶,超氧化物歧化酶 |
| English Keywords:SFPS,leukemia L615 mice,LPO,CAT,SOD |
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| 中文摘要: |
| 本文报道了羊栖菜多糖(SFPS)对L_(615)小鼠全血及肝脾脂质过氧化物(LPO)含量以及对各胱甘肽还原酶(GR)、谷胱甘肽过氧化物酶(GSH—PX)、过氧化氢酶(CAT)、超氧化物歧化酶(SOD)等酶活性的影响。结果表明,SFPS可显著降低L_(615)小鼠全血及肝脾LPO的含量,增加CAT、SOD的酶活性,提示SFPS具有清除L_(615)小鼠体内自由基,抗脂质过氧化作用。本文结果提示,SFPS的这些作用可能是其抗白血病作用的机理之一。 |
| English Summary: |
| This paper reports the effects of the polysaccharide from Sargassum fusiforme (SFPS) on contents of lipoid peroxide (LPO) and enzyme activities of glutathione reductase (GR), glutathione peroxidase (GSH - PX), catalase (CAT), superoxide dismutase (SOD) in whole blood, liver and spleen in leukemia L615 mice. The results show that SFPS remarkably reduces the contents of LPO and increases in the enzyme activities of CAT , SOD in whole blood, liver and spleen in leukemia L615 mice. The authors point out that SFPS may remove the free radicals in the body of leukemia L616 mice and have an effect against lipid peroxidation. This may be one of the mechanisms of SFPS against leukemia. |
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